NFL Week 2 of the 2026 regular season is set with 16 games scheduled from Thursday, September 17 through Monday, September 21. The week begins with a highly anticipated matchup between the Detroit Lions and Buffalo Bills before a busy Sunday featuring 13 games.
NFL Week 2 2026 Schedule
Thursday, September 17
- Detroit Lions at Buffalo Bills — 5:15 PM PT / 7:15 PM CT / 8:15 PM ET.
Sunday, September 20
- Philadelphia Eagles at Tennessee Titans — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Pittsburgh Steelers at New England Patriots — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Minnesota Vikings at Chicago Bears — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Carolina Panthers at Atlanta Falcons — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Green Bay Packers at New York Jets — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- New Orleans Saints at Baltimore Ravens — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Cincinnati Bengals at Houston Texans — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Cleveland Browns at Tampa Bay Buccaneers — 10:00 AM PT / 12:00 PM CT / 1:00 PM ET.
- Jacksonville Jaguars at Denver Broncos — 1:05 PM PT / 3:05 PM CT / 4:05 PM ET.
- Las Vegas Raiders at Los Angeles Chargers — 1:05 PM PT / 3:05 PM CT / 4:05 PM ET.
- Seattle Seahawks at Arizona Cardinals — 1:25 PM PT / 3:25 PM CT / 4:25 PM ET.
- Miami Dolphins at San Francisco 49ers — 1:25 PM PT / 3:25 PM CT / 4:25 PM ET.
- Washington Commanders at Dallas Cowboys — 1:25 PM PT / 3:25 PM CT / 4:25 PM ET.
- Indianapolis Colts at Kansas City Chiefs — 5:20 PM PT / 7:20 PM CT / 8:20 PM ET.
Monday, September 21
- New York Giants at Los Angeles Rams — 5:15 PM PT / 7:15 PM CT / 8:15 PM ET.
Some of the biggest Week 2 matchups include the Lions visiting the Bills on Thursday Night Football, the Bengals facing the Texans, the Steelers traveling to New England, the Dolphins visiting the 49ers and the Commanders taking on the Cowboys.
All kickoff times are listed in Pacific Time, Central Time and Eastern Time for readers in the USA. Dates and times are subject to potential NFL schedule changes.